Obstructive Azoospermia

It is a condition where there is a blockage of the male reproductive tract, leading to a complete absence of sperm in the ejaculate. In obstructive azoospermia, optimal quality of sperms are present in the proximal epididymis but in very poor quality in the distal segments. It is not a very common condition as it is found in less than 1% of all men but in 10-15% of infertile men.

Causes of Obstructive Azoospermia

Obstructive azoospermia may result from epididymal (the coiled tube on the back of each testicle), vasal (the tube that transport sperms), or ejaculatory duct (the tube from which sperm exit in the urethra) pathology. The causes may include:

  • Blockages due to trauma or infection
  • Sexually transmitted diseases (STD)
  • Hernia Surgery
  • Scar Tissue
  • Cystic fibrosis
  • Dysfunction in the process of ejaculation

Treatment for Obstructive Azoospermia

The management of obstructive azoospermia depends on its cause, and it also takes account of any existing female infertility factors. Generally, males with this type of infertility can be treated with surgical correction of the obstruction or by retrieving sperms directly from epididymis or testis, which is then followed by IVF-ICSI.

How Seeds of Innocence can Help

At seeds of innocence, we examine the various causes of obstructive azoospermia, and the suitable treatment is then decided. At our center, we provide both microsurgical vasal reconstruction and sperm retrieval, paired with IVF to males facing infertility issues.


The causes of obstructive azoospermia can be so many. It may be due to infections, inflammation, trauma, rare genetic condition, dysfunction in the process of ejaculation, etc. Your doctor would be able to diagnose the problem accurately.

Yes, the condition can be treated. Depending on the reason, your doctor would administer suitable treatment.

Studies have found that high levels of stress both for short and long-term, can lead to low sperm concentration and counts. However, there are no studies that show it cal lead to zero sperm count. It generally triggers the release of steroid hormones, which may blunt levels of testosterone and sperm production.

You can take multiple measures to prevent azoospermia, which include avoiding exposure to radiation, avoiding activities harmful to reproductive organs, and reducing the intake of medicine that could harm sperm production.

It is found in 1% of all men but approximately 15% of infertile men.