Microarray Testing
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What is Microarray?
Microarray is a highly sensitive genetic test that simultaneously assesses thousands of DNA sequences with high resolution. It detects tiny deletions and duplications or imbalances not detected by routine tests such as karyotyping. Microarray is widely applied in prenatal diagnosis, postnatal diagnosis, and screening for genetic disorders.
Why is Microarray Done?
Microarray testing is recommended for various clinical scenarios, such as:
Why is Microarray Done?
Microarray testing is done to detect small chromosomal gains and losses (copy number variations) that may not be seen on routine karyotyping, in prenatal, postnatal, or miscarriage evaluation.
What Does Microarray Check?
Microarray checks for:
How is Microarray Performed?
The microarray test procedure typically involves:
DNA is extracted from the sample (blood, amniotic fluid, CVS, or tissue).
DNA is labelled and hybridized to a chip containing thousands of probes.
The chip is scanned; software identifies copy number changes.
A genetic report is generated; results are explained with genetic counseling.
How to Prepare for Microarray
Depends on sample type. For blood, minimal preparation. For prenatal microarray, the sample is obtained via amniocentesis or CVS; follow that procedure's preparation.
Understanding Microarray Results
Normal results suggest no significant copy number changes. Abnormal results may show deletions or duplications linked to developmental or other conditions; our genetic counselors explain implications and next steps. Microarray does not detect balanced translocations or single-gene mutations.
Cost of Microarray
Microarray test pregnancy cost and postnatal cost vary by lab and analysis type. Contact us for pricing and to book an appointment.